Among the problems is the low level of henchies (15 vs opponents up to 18-19) and just one healer (Alesia). Enemies are are a good mix of direct damage (trolls, shepherds, spiders) and degeneration (mostly poison or desease, but there are also some wind riders [=mesmer] later on).
My mesmer/necro uses domination + curses (with SS as an elite) to get rid of pulks of trolls and spiders, but for my taste I rely too much on Alesia for healing:
Power Spike
Empathy
Shatter Hex
Leech Signet (2nd interupt, also non spells)
Spiteful Spirit [E]
Parasitic Bond
Reckless Haste
Ressurection Signet
As curses are my main weapon I'd probably be better of with my necro anyway - but then why should my mesmer not be able to do it?
I'm far from fighting comfortably there, let alone solo the area. My problem is, as always, twosided - do enough damage to kill stuff, and get enough protection/ heal to stay alive. I don't care which secondary to use.
Jungle scales and wind riders can strip or shatter enchantments, so a Me/Mo will probably work fine until then.