I found the Assassin class to be immensely useless when it came to PvE. Thus, for some time I fiddled around with my character until I found a build I liked. And I did find one to my liking. My Build, The Critical Palm, as I call it, inflicts massive amounts of damage to a single opponent-nearly 200 damage even if the foe has 100 armor. And the skills used also inflict several conditions that cause further damage. I have not tested this build out extensively, but so far it has been my favorite. I am able to bring my friend’s powerful warrior build to his knees in one-on-one combat, even if I am also killed. Give it a look; give it a try! I’m curious to see how you fellow Guild Wars comrades take to my build.
I also have a link to it on guildwiki: http://gw.gamewikis.org/wiki/A/any_The_Critical_Palm