There are a lot of people lying and making things up here. The AI doesn't cheat and doesn't do things which are technically impossible, and the game engine works just the way it's supposed to work.
Lvl 12 mesmers can interrupt 1/4 cast spells because they have fast casting, as people have said. No human can do that, but there's nothing special about it - their spells cast faster than yours.
The grasps know how to interrupt very well. They will spam the moment they reach you in melee (skullcrack is faster than a normal attack), they will spam during your 3/4 second aftercast to hit chained spells, and they will spam when your enchantments are about to run out. Any human can do this, but other than that, they can't interrupt you. I've been interrupted by Shiro'ken rangers many times, and it was my fault every time, because I did one of those things.
So, again, the AI doesn't do crazy, impossible things without any explanation, and people should stop making up stories.
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