Attribs:
Deadly Arts: 12+1+3
Dagger Mastery: 8 +1
Shadow Arts: 7
Critical Strikes: 8
Quips:
Radiant Armor, Attunement Runes, Superior Vigor Rune, and of course the matching attribution runes
Daggers can have whatever mod you want, but Zealous tang is recommended. I use 15^50 and +30 health, but again, up to you.
Skills:
[skill]Jagged Strike[/skill][skill]Entangling Asp[/skill][skill]Wild Strike[/skill][Vampiric Assault][skill]Impale[/skill][Signet of Deadly Corruption][skill]Feigned Neutrality[/skill][skill]Resurrection Signet[/skill]
Okay, You may think this is energy heavy, but I can run several chains with 37 energy just fine (if the last 3 are recharged, otherwise you whack anyway :P). So it's doable without needing more than 2 attunement runes and all radiant armor.
So what can this build tackle? EVERYTHING. Sure, you have problems with monks and healers, but other than that, it takes down everything. With the current setup, the Signet deals 111 damage. Just choose a target and away you go :O What makes this build interesting is that it's a mix of both attacks and signets/spells. So if your person is starting run and you've already cleared up to vampiric assault, then Impale and Deadly Corruption are still executable.
Same with Entangling Asp. If after Jagged they start to run, just hit it and try to catch up with them to at least get Wild and Vampiric on and it's over.
Pretty simple. I saw a similar build with the signet but thought it was different enough to have it's own thing

Possible Optional Skills:
[skill]Temple Strike[/skill] (just change attribs slightly and replace Entangling Asp)
To replace Res Sig for AB:
[skill]Blinding Powder[/skill]
[skill]Mending Touch[/skill]
[skill]Signet of Toxic Shock[/skill]
Counters:
Blind (somewhat)
anti-melee
Backfire (somewhat)
Blocks...sorta (wild strike will kill any stances)
other standard stuffness
Edit:
I'm still trying out stuff, but that's the main jist o_O
*trying Virulence instead of Entangling Asp and with Toxic Shock*