Sin Rune and Insignia?

Hey guys what is a good rune and insignia for a Sin?

Generally speaking, the runes you run are dependent on the build. But, uhh...
Vitae [+health]
Attunement [+energy]

And then whatever attribute-specific stuff you think is necessary for your build.

Insignia:
Radiant [+energy]
Survivor [+health]
Nightstalker's [+15 armor while attacking]

Runes are dependent on your build; some builds make sense running 16 Shadow Arts, most don't. So assuming that you're running with daggers, generally speaking, something like the following should work okay (once you get to level 20 and get all your attribute points):

13 Critical Strikes (11+1 [rune] +1 [mask])
12 Dagger Mastery (11+1)

That leaves you 10 points in anything else you want. For more information on attribute point spending, read this.

Also get the best Vigor rune [+health] you can get your hands on. I hope all that helps, but your question was poorly worded and vague.