Increase clocks at 5mhz intervals and test with a game or benchmark(i trust games more), if you're still stable go and increase 5mhz more untill you start getting lower FPS/artifacting(usually white"snow" pixels on screen) then lower the clocks to their last stable point.
Depending on the brand of the card(eVGA,XFX,BFG) some come with better coolers and heat wont be a problem. If it becomes one stop back by and we'll pick you out a nice Zalman to slap on it.
8800GT's can gain quite a boost with just over clocking
EDIT: There may be a tab to "Detect best clock settings" or something along those lines, their idea of "best" is usually WAY too high.