As far as profession goes there are some easier than others, some are also more used in elite areas if you come to play the game for alot of hours.
The casters that are used the most in elite areas are
Monk (depends)
Ritualist (depends)
Elementalist (bonder/nuker)
(Mesmer) (mimic other casters, mixed builds and siggieway for DoA)
The physicals that are used the most are
Assassin (Shadowform)
Warrior (skills; Hundred Blades, Save Yourselves)
Those 5 will make it a bit easier to play, the easiest to get into elite pug's (pick up group) would be monk and sin.
I'd recommend playing what you find fun. As far as simplicity is concerned though: Ritualist, Elementalist, Mesmer (this is imo) and assassin the easiest to play the game through (sin is locked down to a specific build which basically makes it to an aggroherder - view a guide/turtuorial on a videosite).
I'd highly recommed joining a mid sized guild (least 20 active - that's daily, members), it will help alot. IF you are only in to gain the titles for GW2 then I'd recommend going for sin, rit, monk or mesmer as profession.
See to that you got these links;
The Wiki and some useful links (recall that the wiki's are somewhat open and doesnt cotain all information for one reason or another).
http://wiki.guildwars.com/wiki/Main_Page
Campaign travel:
http://wiki.guildwars.com/wiki/Campaign_travel
Maps:
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http://wiki.guildwars.com/wiki/List_of_maps
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