After running into locked gates trying to move from city to city (very frustrating) this helped me.
Delete all GW files on computer and break CD.... J/K
Deleted all factions quests I had taken (about 6 or 9). Follow only the primary quests.
*edit: Ya, what Mindtrust said above

Seems they don't want you to have to think much about ways to go through the game. Just have to stick with the primary quest and follow the green arrow.