Just as a suggestion, if you're deciding playing an entirely new character concept, I highly advise starting it in Tyria. Prophecies' skills are referred to as "core" for a good reason; they are core to the game. They were the original skills, and are the backbone of the Guild Wars game. Factions' skills are basically new ideas that compliment old skills or encourage new build ideas. If it's a Monk, the skills obtained in Tyria are invaluable - Word of Healing, Mark of Protection, and so on. How could you play a Mesmer without knowing the use of Ineptitude? The same goes for every class, the core elite skills and regular skills give you the simplest, most direct concept of what that class is about. Also, you will end up with a wealth of skills just by completing quests and accepting the rewards -
for free!
Outside of your starter skills obtained in a few quests in Cantha, you are forced to buy every skill after that point.
Furthermore, Cantha is obviously driven toward high-level content, and immediately rushes you to level 20 in less than ~10 hours of gameplay. So why not enjoy your game time, taking your time to level up and exploring lower-level areas? By starting in Tyria and not having access to the Shing Jea island missions, you really aren't missing anything. But by starting in Cantha and not having access to the first 7 Tyrian missions, you're missing out on
a lot. Plus, Pre-searing Ascalon is beautiful!
So for starting a new character,
Tyria > Cantha - by far. Hopefully this will aid you in your decision.
