Here I go with the questions again...
Does it mess up when playing DVD's or other video?
Did you run the Direct X tests (run "dxdiag" from the command prompt)?
Quote:
Reinstalled the drivers, made sure the card wasn't loose. Tried cleaning things up.
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Does "drivers" include the latest version of DX?
http://www.microsoft.com/windows/directx/default.mspx
(Reminds me... I need to update all my stuff too...

)
Since it happens in other games I'd be inclined to rull out that your Guild Wars textures got messed up.
Yaaaayyyy, no long downloads...
Boooooooo, it's likely a hardware issue.
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Did you try taking the graphics card out and cleaning off the contacts where it plugs in? (taking all precaution to handle it carefully of course)
Just pull out the card and run a standard pink pencil eraser over the contacts. Rub about as hard as if you are trying to get dark letters off a page of paper. Brush the eraser dust off and reseat it in the slot.
Sometimes there is a thin flim of corosion that you can't even see it (that's how it was with the satellite system I mentioned before) but it is enough to mess with the signal. Heck, sometimes just pulling the card out of the slot and putting it back in is enough to scrub the contacts and give it better contact.
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I'm thinking you could also try swapping out video cards with a different computer to see if it's the current card that is at fault. Short of going out and buying a new video card, it's the next thing to try.
Luckily GW is new/good enough code that it's tolerant of many older/less expensive/non-ultra-high-performance cards. Even if you have to get a new one you should be able to do so without going broke in the process.
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Hope we can nail it down... nothing worse than computer issues taking away yer fun time.