If you've seen Siy the Steel Fist in RA, yeah, that was me

Full Shrouded is pretty much needed to go through the whole combo without pause, so take it if you can.
A +5 energy dagger with 1/1 Zealous is your best choice.
I prefer a +5 armor vs all or +30 health grip, but a +20% enchant might work for you as well.
11+2 - Dagger Mastery
11 - Deadly Arts (or more if you want to put a minor rune in there)
10+2+1 - Critical Strike
Mark of Instability
Iron Palm
Palm Strike {E}
Death Blossom
Falling Spider
Horns of the Ox
Sharpen Daggers
Ressurection Signet
Ok well first off, this build is really fun for RA, TA, etc. and even for PUGs (if you can get into one as a 'sin).
Enchant yourself with Sharpen Daggers for an extra -3 degen to compliment the -4 degen with falling spider. Follow through with Iron Palm for damage and a KD, then immediately smack-down with Palm Strike {E}. By now they should be rising again, and then KD them once more with Death Blossom and add that poison with Falling Spider. (Death Blossom KDs the target because of MoI). So now your target is below 50% health, suffering -7 degen, and has just been KDed twice. Sounds pretty fun right? WRONG!!..well yes...it is fun, but it gets better. Just when they think they can get up and finally run again, you'll snare them with Horns of the Ox and that should finish them up.
This can easily take down warriors due to the ~100 armor ignoring damage. Eles and your long cast times beware!