In-mission crashing

I've done the Abaddon's Mouth mission twice in a row now, and each time Guild Wars crashes at the end. It's not crashing at the same area, so I'm guessing it's because of how long the game has been going on or something... It's really starting to get on my nerves, especially if I can't get past that mission. Has anyone heard of this before?

I'll bump this with an update instead of creating a new thread. This event has now happened as early as 10-15 minutes into the game, and with multiple characters. Basically, the screen goes black and my system reboots.

I do have some heating issues...

Motherboard 39 °C (102 °F)
CPU 31 °C (88 °F)
Aux 49 °C (120 °F)

... even with 7 fans (some of which are controlled by a Thermaltake Hardcano 10 unit which has the fan speeds maxed.) I've got a sinking feeling that it is a temperature problem, but I want to get the other possibilities out of the way before I go dropping more money on my box.

I did try updating my ATI Radeon X700 Pro's drivers with the newest Catalyst pack from the ATI website (I believe it was 5.11 or something) but that ended up being unable to load whenever I rebooted, so I reverted back to my current driver, identified as version 8.102-050201 a-020972c-ATI. I'm also using DirectX 9.0c, though I have never encountered any problems with it.

If anyone knows of a solution to this problem I would be extremely grateful.

Sorry to say, but it's most likely your heat. My sister's laptop does the same thing when she plays maple story or runescape and her cpu sometimes goes to 61 degrees Celceius! You might want to consider moving or elevating your comp a little or switching its case to allow more air flow or consider (if you got the cash) to get a liquid cooling system instead of fans. Just my 2 cents