best i can do is explain it to you.
first things first, always carry with you 4 obsidian keys at a time, some runs i see more than 4 chests in one run.
You need a standard running build that includes:
Charge(e)
Spirint
Diciplined Stance
Endure Pain
Purge Conditions
Smite Hex
Healing Signet
Rebirth
Reason i carry rebirth is sometimes i go down with a partner, and we travel in different directions and scout fow faster, we communicate via teamspeak till we find chests, we open them, the when opening them you need to identify what kind of chest it is, example, if the chest drops a purple item, then warn your partner that its a purple chest, and will only reveal purples no matter how many times you open it.
If you find a gold item chest that drops a offhand weapon, like a storm artifact, then the chance it will be some type of offhand weapon for your partner, but i've been proven wrong before, i got a protective icon and my partner had a chaos axe, a useless one though so i was happy haha.
Best items ive found fow, chaos axe 15>50 req 9, soon as i sold this puppy, all my worries went away, i could finally buy 15 armor set for a few of my characters, and a fow helmet for my warrior, also the chest where i found this axe was 30 seconds away from where you spawn in fow.
Anyway to start off, you basically run past all the shadow army at the start, dont worry they are your friends compaired to the skeleton army, when you get the nack of it, you dont even have to use endure pain past them, the only time you use endure pain is when you run past skele mobs, they'll drain your energy and freeze you while the beserkers own you from behind, so you charge in, endure pain, smite hex, you might get cry of fustration on your smite hex, its the most annoying part, these ether skeletons can interrupt a 1/4 second purge conditions. so hopefully you can get around them without you dying, u should have enough nrg left to use sprint and away you go again.
Anyway the first place to check for chests is the great battlefield, which is where those lich dragons are, scout all around there, in the time ive been down there, these chests do spawn in specified random locations, but these random locations are not very random lol, example say if a chest spawns in a certian spot, remember that location for next time, mabye a few more runs down the track it will spawn in that location, when you spent as many times down there running you start to see the pattern. anyway i think i type too much, hopefully u can figure the rest yourself. gl
Do not carry enchantments in fow if your running solo, they will be stripped before you can say "wtf"