I've added a GuildWiki build page for this build: http://gw.gamewikis.org/wiki/N/Mo_Boss_Farmer
The wiki page details how to make the build and also gives a list of bosses known to be farmable with this build.
For specific instructions on how to kill each boss please continue reading through this Guru thread.
Well I was neglecting my poor necro, Atra Lucia, because I was on my monk so much farming Shiro'ken. So I decided to see what PS/SB could do for Atra.
The Bad News:
You can't solo Shiro.
The Good News:
Ssyn Coiled Grasp can be farmed much more easily on a PS/SB Necro than a 55hp iNecro. Of course it all comes down to Blood and Protection.
Here's what you'll need:
1. +5e/20% longer enchant weapon. I prefer using Rajazan's Fervor because it's nice looking, but a Totem Axe will get the job done.
2. 20/20 Offhand for Blood or Prot. Honestly it doesn't matter. You just want the extra energy. I have a blood offhand that I use even though the build doesn't use any blood spells. If you have a 20/20 prot offhand then by all means use it. It won't matter though, because both Prot spells are 1/4 cast and reasonablly fast recharge. Still, I'd go prot if you're new to farming.
3. 15AL chest, arms, pants and shoes from Shing Jae.
4. 60AL head scar with Superior Blood Rune and intrinsic +1 to Blood Magic.
The build (no elite!)
Spirit Bond
Protective Spirit
Touch of Agony
Wallow's Bite
Vampiric Bite / Vampiric Touch (can leave open if you want)
Plauge Touch
Essence Bond
Balthazar's Spirit
Attributes:
16 (12 + 1 + 3) Blood
12 Protection

The Farm:
1. Leave from Jade Flats to the Archipelagos.
2. Pre-cast Essence Bond and Balthazar's Spirit
3. Get a blessing from the Priest at the shrine. (optional)
4. As you run up the stairs to the first mob (2 Kappas and a Naga Rit) cast PS/SB.
5. Run through to the next group which are typically 2 Naga warriors, a Naga archer and a Naga Rit.
6. Run through this group as well and head over the bridge. Be careful to renew PS/SB as needed.
7. Past the bridge you should see Ssyn. Run to Ssyn while renewing PS/SB.
8. As you aggro the other Naga in Ssyn's mob make sure to get right next to Ssyn. Keep renweing PS/SB.
9. Now... start your touching. You will get your touches interrupted a lot. This is normal and expected. In fact it's desirable. The Naga Warriors will use their energy to interrupt your touch skills which recharge pretty quickly. After you see a touch interrupted refresh either PS/SB. Always follow an interrupted touch skill with a refresh of PS/SB. I refresh PS/SB earlier than needed because I don't want to be at the end of either and have my refresh interrupted. Energy is not an issue. You are holding aggro of at least 8-12 Nagas plus Ssyn.
9. Keep touching/refreshing until Ssyn is dead.
10. Claim loot if any.
NOTE: If you get Dazed by Concussion Shot (which hasn't happened to me yet) then Plague Touch it onto Ssyn and keep going.

This farming method is likely to trigger anti-farming code because you are only killing one foe near a map transition. Do not post here asking me why you never got the drop when you farmed Ssyn 150+ times. Farm Ssyn 10 times and move on to something else if you don't get the drop. Rotate your crops people!
Regards,
MelechRic