here's my system.......
A64 3200+ NewCastle Core @ 2.2ghz
Asus K8V SE Deluxe
eVGA 6800 Ultra
Kingston Hyper X PC-3500-2\512 sticks
Western Digital 80gig HD
No Sound Card-Useing OnBoard Sound
500watt Ultra X-Connect PSU
i unoverclocked my system and ran Memtest 86 on my ramm for over 10 hours and Memtest 86 didnt find any errors on my ramm. i swapped out harddrives and replaced all my ribbon cables going to my devices.......nothing....and i do mean nothing a have tried has fixed my problem. GW still locks up within 5 minutes of playing. im not buying another computer just to play a $50 video game. guys....i think we all made a big mistake buying this game. every other game i have runs perfectly, no crashes, no lockups. GW is the only game i have that doesnt want to work.
P

However it would be useful if those experiencing the problem make it clear that they have tested their memory and the cpu heat has been checked. I would recommend reporting it to Arena net if you haven't already - they are pretty sound and at least the issue does get properly recorded. Load of other stuff which can be done as well - my post earlier pretty much covered the initial recommendations and my own from Arena net.
this game is more bugged than the beta