Possibly with severe artery (or some condition) on two spiders around you at the same time, you may never need to use Healing Signet. Using I Will Survive! and Victory is Mine!.
In 30 second cycle, there would be:
30 seconds of -4 regen from poison (240 hp degeneration).
Should be 0 damage from attacks
2 of 50 x 2 or so hp heals from Victory is Mine! (and 2 of 5 energy)
10 seconds of +3 regen from I Will Survive! (60hp regeneration, for 5 energy).
That's +20hp (and 5 energy) every 30 seconds... if you do it immediately after cooldown.
But you might still want Healing Signet getting to the coast and spiders, so I don't really know.
Hopefully no calculation errors.
l



